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Bruno Stricker, MB PhD


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Contact

Bruno Stricker, MB PhD

Phone+31 (0)10 70 44294
Emailb.stricker@erasmusmc.nl or bh.stricker@igz.nl

Biographical Sketch

 

POSITION TITLE: Professor of Pharmaco-epidemiology


EDUCATION/TRAINING    

 
Institution and location Degree Completion Date Field of Study
Leiden University Drs 1971-1977 Medicine
Erasmus University PhD 1987 Drug-induced hepatic injury

 

Positions and Honors

1. Positions and employment:

  • Professor of Pharmacoepidemiology, Department of Epidemiology, Erasmus Medical Center, Rotterdam
  • Coordinating Inspector for Pharmacovigilance, Inspectorate of Healthcare, the Hague

 

2. Other relevant experience and professional memberships:

  • Registered clinical epidemiologist
  • Registered clinical pharmacologist
  • Member of the Dutch Health Council

 

3.Honors and awards:

Best tutor of the year 2012, Erasmus University Medical School

Contributions to Science

My ten most contributing (most significant) publications [within past 5 years]:

  1. den Hoed M, Eijgelsheim M, Esko T, et al. Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet 2013;45:621-31. [impact factor: 35.2]
  2. Wilk JB, Shrine NR, Loehr LR, et al. Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction. Am J Respir Crit Care Med 2012;186:622-32. [impact factor: 11.0]
  3. Ellinor PT, Lunetta KL, Albert CM, et al. Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nat Genet 2012;44:670-5. [impact factor: 35.2]
  4. Lucena MI, Molokhia M, Shen Y, et al. Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles. Gastroenterology 2011;141:338-47. [impact factor: 12.8]
  5. Sotoodehnia N, Isaacs A, de Bakker PI, et al. Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. Nat Genet 2010;42:1068-76. . [impact factor: 35.2]
  6. Eijgelsheim M, Newton-Cheh C, Sotoodehnia N, et al. Genome-wide association analysis identifies multiple loci related to resting heart rate. Hum Mol Genet 2010;19:3885-94. [impact factor: 7.7]
  7. Pfeufer A, van Noord C, Marciante KD, et al. Genome-wide association study of PR interval. Nat Genet 2010;42:153-9. . [impact factor: 35.2]
  8. Benjamin EJ, Rice KM, Arking DE, et al. Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry. Nat Genet 2009;41:879-81. . [impact factor: 35.2]
  9. Vasan RS, Glazer NL, Felix JF, et al. Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data. JAMA 2009;302:168-78. [impact factor: 29.9]
  10. Teichert M, Eijgelsheim M, Rivadeneira F, et al. A genome-wide association study of acenocoumarol maintenance dosage. Hum Mol Genet 2009;18:3758-68. [impact factor: 7.7]

 

Median impact factor of my publications: 32.0

Median impact factors for my own field(s): 6.1

 

The top 3 leading Journals in my field are:

  1. Clinical Pharmacology & Therapeutics [impact factor: 6.8]
  2. Clin Pharmacokinetics [impact factor: 6.1]
  3. Drug Metabolism Review [impact factor: 5.8]

Research Support

Grant Principal Investigator

Amount

Year of award

Status

(Title, grand ID, funding agency)

 

 

 

 

 

Resistence to antimicrobial medicines; VWS/IGZ

250 kEuro

2013

ongoing

Biomarkers for improving the cost-effectiveness and safety of pemetrexed; ZonMw Dossiernr. 152001017

 

 

434 kEuro

2011

ongoing

Risk factors for adverse reactions in elderly; VWS/IGZ

250 kEuro

2011

ongoing

Marginal structural models for the analysis of time-dependent drug use in observational studies; ZonMw
Dossiernr. 152002036

 

125 kEuro

2011

ongoing

Cardiovascular medication and the risk of depression; ZonMw Dossiernr. 100002008

150 kEuro

2010

completed

Genetic determinants of COPD; VWS/IGZ

250 kEuro

2010

completed

Pharmaco-epidemiology as a tool in pharmacovigilance: studying cancer as adverse drug reaction; VWS/IGZ

250 kEuro

2009

completed

Sex differences in cardiovascular drug response; VWS/IGZ

250 kEuro

2009

completed

Effectiviteit en doelmatigheid van het gebruik van griepvaccinaties op landelijke schaal door ouderen
Dossiernr. 22000090

 

190 kEuro

2009

completed

Interaction between genetic polymorphisms of the multidrug resistance (MDR1) gene and digoxin as determinants of diastolic dysfunction and increased cardiovascular and total mortality; ZonMw Dossiernr. 94800014

 

 

208 kEuro

2008

completed

Acute pancreatitis toegeschreven aan geneesmiddelen; ZonMw Dossiernr. 92003074

 

150 kEuro

2007

completed

Association  of common  NOS1AP  allele variants with  QTc

interval  prolongation  ard sudden cardiac  death,  and possible interaction  with QT prolonging  drugsNOS1AP-gene and sudden cardiac death. Nederlandse Hartstichting

254 kEuro

2007

completed

 

 

 

 

Subtotal

2.761 kEuro

 

 

 

 

 

 

Grant Co-applicant

Amount

Year of award

Status

“NGI-NCHA: Netherlands Consortium Healthy Aging”

            NWO-NGI, 2008-2014 (project nr. 050-060-810)                                                                                                                                    €  13.500.000,=

 (Title, grand ID, funding agency)

13500 kEuro

 

ongoing

Subtotal

16261 kEuro

 

 

 
 
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