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Trudy Voortman


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Trudy Voortman

Phone+31 (0)10 70 44214
Emailtrudy.voortman@erasmusmc.nl

Biographical Sketch

POSITION TITLE: Postdoctoral researcher


EDUCATION/TRAINING
Institution and location Degree Completion Date Field of Study
Wageningen University and Research Center BSc 2009 Nutrition & Health
Wageningen University and Research Center MSc 2011 Molecular Nutrition
Netherlands Institute for Health Sciences MSc 2014 Epidemiology
Erasmus University Medical Center PhD 2015 Nutritional Epidemiology

Personal Statement

I am a nutritionist and epidemiologist, working as postdoctoral researcher at the department of Epidemiology of Erasmus MC University Medical Center. My research focuses on the role of nutrition in health throughout the life course, with a particular emphasis on nutrition in early life and on obesity and cardiometabolic health. For my studies I use data from the population-based cohorts the Rotterdam Study (n~15,000 elderly) and the Generation R Study (n~10,000 women and their children), and I perform several systematic reviews and meta-analysis. My research interests include dietary patterns analysis, macronutrient substitution models, fatty acids and fatty acid patterns, effects of diet and lifestyle on insulin sensitivity and the development of diabetes, body composition (lean, fat and bone mass), blood lipids, vitamin D, epigenetics as potential intermediate between nutrition and health, gene-diet interactions, and maternal and infant nutrition. I have so far published 32 international scientific papers and 1 book chapter and currently lead a research line including 5 PhD students and 6 Master students.

1. Voortman T, Leermakers ET, Franco OH, Jaddoe VW, Moll HA, Hofman A, van den Hooven EH, Kiefte-de Jong JC. A priori and a posteriori dietary patterns at the age of 1 year and body composition at the age of 6 years: the Generation R Study. Eur J Epidemiol. 2016 Jul 6;PubMed PMID: 27384175.
2. Voortman T, Braun KV, Kiefte-de Jong JC, Jaddoe VW, Franco OH, van den Hooven EH. Protein intake in early childhood and body composition at the age of 6 years: The Generation R Study. Int J Obes (Lond). 2016 Jun;40(6):1018-25. PubMed PMID: 26975442.
3. Voortman T, van den Hooven EH, Braun KV, van den Broek M, Bramer WM, Chowdhurry R, Franco OH. Effects of polyunsaturated fatty acid intake and status during pregnancy, lactation, and early childhood on cardiometabolic health: A systematic review. Prog Lipid Res. 2015 Jul;59:67-87. PubMed PMID: 26025302.
4. Voortman T, van den Hooven EH, Heijboer AC, Hofman A, Jaddoe VW, Franco OH. Vitamin D deficiency in school-age children is associated with sociodemographic and lifestyle factors. J Nutr. 2015 Apr;145(4):791-8. PubMed PMID: 25833782.

Positions and Honors

Positions and Employment:
2015-present: Postdoctoral scientist, Department of Epidemiology, Erasmus MC, the Netherlands.
2015: Visiting scientist, Department of Nutrition, Harvard School of Public Health, Boston (7-month visit).
2015: Visiting scientist, Department of Nutrition, Nestlé Research Center, Lausanne (1-month visit).
2012-2015: PhD scientist, department of Epidemiology, Erasmus MC, the Netherlands.
2011-2012: Nutrition Scientist, Unilever Research & Development, the Netherlands

Other Experience and Professional Memberships:
2013-present: Board Member, Dutch Academy for Nutrition Sciences
2015-present: Member, Nutrition Society
2014-present: Member, American Society for Nutrition
2008-2010: Board member, Education Institute Wageningen University

Honors:
2016: World Congress for Pediatric Gastroenterology, Hepatology and Nutrition (WCPGHAN) Young Investigator Award
2014: Netherlands Institute for Health Sciences Award for best Master’s thesis 2013-2014
2011: Awarded MSc-degree cum laude
2009: Awarded BSc-degree cum laude

Contributions to Science

1. The importance of nutrition in early childhood for health. In several publications, I found that dietary factors in early childhood were associated with later growth, body composition and cardiometabolic health. For this research, I used several approaches to study diet, including macronutrient substitution models to examine macronutrient composition of the diet and dietary pattern analyses to define diet quality and derive dietary patterns best predicting a certain health factor. For example, I found that a high protein intake in early childhood is associated not only with a higher BMI, but specifically with a higher body fat mass, and that dietary patterns at an age as early as 1 year can predict later body composition.

Relevant papers:
a) Voortman T, Leermakers ET, Franco OH, Jaddoe VW, Moll HA, Hofman A, van den Hooven EH, Kiefte-de Jong JC. A priori and a posteriori dietary patterns at the age of 1 year and body composition at the age of 6 years: the Generation R Study. Eur J Epidemiol. 2016 Jul 6;PubMed PMID: 27384175.
b) Voortman T, Braun KV, Kiefte-de Jong JC, Jaddoe VW, Franco OH, van den Hooven EH. Protein intake in early childhood and body composition at the age of 6 years: The Generation R Study. Int J Obes (Lond). 2016 Jun;40(6):1018-25. PubMed PMID: 26975442.
c) Braun KV, Erler NS, Kiefte-de Jong JC, Jaddoe VW, van den Hooven EH, Franco OH, Voortman T. Protein intake in early childhood and growth. J Nutr. 2016.

2. The high prevalence of vitamin D deficiency and its determinants and consequences. I found that almost one-third of 6-year-old children in Rotterdam were vitamin D deficient, with 6% being severely vitamin D deficient. Of children with a non-Dutch ethnic background, more than half had vitamin D deficiency. Other important determinants were related to lifestyle (playing outside, diet quality, watching television) and family sociodemographic factors such as family income. Also among elderly in Rotterdam, vitamin D deficiency is highly prevalent, with 57% having vitamin D deficiency. Vitamin D deficient subjects were found to be at higher risk of obesity, myopia, and dyslipidemia.

Relevant papers:
a) Voortman T, van den Hooven EH, Heijboer AC, Hofman A, Jaddoe VW, Franco OH. Vitamin D deficiency in school-age children is associated with sociodemographic and lifestyle factors. J Nutr. 2015 Apr;145(4):791-8. PubMed PMID: 25833782.
b) Vitezova A, Muka T, Zillikens MC, Voortman T, Uitterlinden AG, Hofman A, Rivadeneira F, Kiefte-de Jong JC, Franco OH. Vitamin D and body composition in the elderly. Clin Nutr. 2016 May 14. pii: S0261-5614(16)30050-4. PubMed PMID: 27346177.
c) Miliku K, Voortman T, Franco OH, McGrath JJ, Eyles DW, Burne TH, Hofman A, Tiemeier H, Jaddoe VW. Vitamin D status during fetal life and childhood kidney outcomes. Eur J Clin Nutr. 2016 May;70(5):629-34. PubMed PMID: 26695721.
d) Vitezova A, Voortman T, Zillikens MC, Jansen PW, Hofman A, Uitterlinden AG, Franco OH, Kiefte-de Jong JC. Bidirectional associations between circulating vitamin D and cholesterol levels: The Rotterdam Study. Maturitas. 2015 Dec;82(4):411-7. PubMed PMID: 26358932.

Research Support

2016: Nestlé Ltd./Nestec – Childhood nutrition & growth, body composition, and cardiometabolic health (€184,000).
2015: Albert Renold Fellowship, European Foundation for the Study of Diabetes – Dietary patterns and the development of type 2 diabetes (€8,000)

 
 
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